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1.
PLoS One ; 16(9): e0255525, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34469435

RESUMO

PURPOSE: To identify mechanical factors, as well as patients' biometric and surgeons' experience factors that correlate with the FF incidence in microkeratome (MK)-assisted LASIK and to construct a predictive model based on these parameters. METHODS: 55,700 consecutive LASIK treatments of 28,506 patients between January 2017 and April 2020 done by 50 surgeons in 10 centers, all with Sub Bowman Keratome (SBK) and 90µ head (OUP) were analyzed retrospectively for the incidence of FF and their correlation to mean keratometry, central corneal thickness, MK ring height and stop, as well as surgeons' experience. A prediction model was built and tested for sensitivity and specificity. RESULTS: The incidence of FF using the SBK MK was 0.276%. Risk factors were low central corneal thickness, very flat (-1) or very thick (+2) ring height, and higher stop values (p<0.001). Mean keratometry and low surgeon experience were not correlated to FF incidence. A prediction model with a cut-off FF risk of 0.274%, a 76% specificity, and a 73% sensitivity was applied. CONCLUSIONS: Free flaps are rarely seen in modern MK LASIK. However, the incidence of this complication using the SBK MK increases using higher stop values, very thick and very thin MK rings, and in eyes with thin corneas.


Assuntos
Astigmatismo/cirurgia , Retalhos de Tecido Biológico/estatística & dados numéricos , Hiperopia/cirurgia , Ceratomileuse Assistida por Excimer Laser In Situ/efeitos adversos , Modelos Estatísticos , Miopia/cirurgia , Complicações Pós-Operatórias/epidemiologia , Adolescente , Adulto , Idoso , Biometria , Estudos Transversais , Feminino , Alemanha/epidemiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/patologia , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Adulto Jovem
2.
Jt Dis Relat Surg ; 32(2): 531-535, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34145835

RESUMO

Surgical site infection is a challenging situation for all types of surgeons. Extensive debridement with or without implant removal can create soft tissue defects. A well-vascularized, adequate soft tissue is needed to cover the wound and to fill the dead space for proper healing. Herein, we describe our approach to a large posterior trunk defect with dead space and our solution to manage an intraoperative complication using a free-style deepithelialized propeller flap.


Assuntos
Retalhos de Tecido Biológico/estatística & dados numéricos , Infecção da Ferida Cirúrgica/cirurgia , Cicatrização , Idoso , Humanos , Masculino , Turquia
3.
J Plast Reconstr Aesthet Surg ; 74(10): 2486-2494, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33935007

RESUMO

INTRODUCTION: There appears to be an association between preoperative opioid use and postoperative complications. We sought to determine whether patients with a history of chronic opiate use (defined as 3 months or more of sustained use) prior to undergoing free flap surgery have higher rates of 30-day complications. METHODS: A retrospective review of patients undergoing free flaps from 2015 to 2020 was performed. Patient characteristics were analyzed, including daily preoperative dose of opiates, which were then converted to morphine milligram equivalents; intra-operative variables such as estimated blood loss and operating room time; and 30-day outcomes, including wound and flap complications, return to the operating room, and readmissions. RESULTS: One hundred fifty-five patients received 160 free flaps. Of these flaps, 50/160 (31%) were performed on patients with an opiate prescription for at least three months prior to surgery. Using multivariable analysis, morphine milligram equivalents, a surrogate for opioid dose, were significantly associated with flap complications (odds ratio (OR) 1.011, 95% confidence interval (CI) 1.003-1.020, p<0.01), partial flap loss (OR 1.010, 95% CI 1.003-1.019, p<0.01), and surgical site infections (OR 1.017, 95% CI 1.007-1.027, p<0.01). Additionally, estimated blood loss was associated with partial flap loss (OR 4.838, 95% CI 1.589-14.728, p<0.006), and operating room time was also associated with flap complications (OR 1.337, 95% CI 1.152-1.150, p<0.01). CONCLUSION: Chronic preoperative opioid use is common for free flap surgery, and according to our single-center experience, higher daily doses are a risk factor for flap complications and surgical site infections. These findings add to the growing body of evidence that opioid use is a modifiable risk factor that may increase surgical morbidity.


Assuntos
Retalhos de Tecido Biológico , Morfina , Procedimentos de Cirurgia Plástica/efeitos adversos , Complicações Pós-Operatórias , Período Pré-Operatório , Infecção da Ferida Cirúrgica , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/efeitos adversos , Relação Dose-Resposta a Droga , Feminino , Retalhos de Tecido Biológico/efeitos adversos , Retalhos de Tecido Biológico/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Morfina/administração & dosagem , Morfina/efeitos adversos , Duração da Cirurgia , Avaliação de Processos e Resultados em Cuidados de Saúde , Complicações Pós-Operatórias/classificação , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Procedimentos de Cirurgia Plástica/métodos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Medição de Risco , Fatores de Risco , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/etiologia , Estados Unidos/epidemiologia
4.
J Plast Reconstr Aesthet Surg ; 74(10): 2479-2485, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33879412

RESUMO

BACKGROUND: Free flap complications are generally rare, but not negligible since they may exert paramount impact on both patients and care providers. The aim of the study was to identify risk factors for reexploration and assess predictors associated with increased salvage rates. METHODS: A retrospective cohort study was conducted for free flaps performed between 2006 and 2015. Patient demographics, indications and flap types were analyzed together with complications and time to reexploration. RESULTS: Among 547 consecutive free flaps, 11.5% required acute reexploration. Hematoma together with vascular compromise was the main cause (41.9%) for reexploration, followed by hematoma only (19.4%), venous (16.1%) and arterial (6.5%) thrombosis. Hematoma was associated with an increased risk for concomitant vascular complication (p < 0.02). The incidence of total and partial flap necrosis was 3.5% and 3.7% respectively. There was an overall 71.4% salvage rate. The median time from detection of a compromised flap to reexploration was 3.0 h. Significantly higher salvage rates were observed for cases reexplored within (82.4%) compared to after (57.1%) 3.0 h (OR 3.50 (95% CI 1.10 to 11.13, p = 0.034)). CONCLUSIONS: The current study highlights the importance of early intervention, including evacuation of hematomas that may lead to vascular compromise. Adequate monitoring of venous outflow was found necessary to improve flap salvage rates, whereas arterial complications were mainly related to persistent arterial injury in traumatized extremities with reduced salvage rates. Free flap surgery requires trained staff and immediate access to operating facilities to ensure high flap survival rates.


Assuntos
Retalhos de Tecido Biológico , Hematoma , Procedimentos de Cirurgia Plástica/efeitos adversos , Complicações Pós-Operatórias , Trombose , Intervenção Médica Precoce/métodos , Feminino , Retalhos de Tecido Biológico/efeitos adversos , Retalhos de Tecido Biológico/irrigação sanguínea , Retalhos de Tecido Biológico/classificação , Retalhos de Tecido Biológico/estatística & dados numéricos , Hematoma/etiologia , Hematoma/prevenção & controle , Hematoma/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/patologia , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Fluxo Sanguíneo Regional , Reoperação/métodos , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Risco Ajustado/métodos , Fatores de Risco , Terapia de Salvação/métodos , Suécia/epidemiologia , Trombose/etiologia , Trombose/prevenção & controle , Trombose/cirurgia , Tempo para o Tratamento/estatística & dados numéricos
5.
J Plast Reconstr Aesthet Surg ; 74(3): 475-479, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-32972878

RESUMO

BACKGROUND: Enhanced recovery after surgery (ERAS) is increasingly used in plastic surgery to optimize patient care. Mitigating the risk of postoperative complications is particularly important in patients with risk factors, such as obesity. The objective of this study is to evaluate the impact of the ERAS pathway in patients, stratified by BMI, undergoing free flap breast reconstruction on length of stay and complications. METHODS: A retrospective review of all patients who underwent abdominally based free flap breast reconstruction from January 2014 to December 2017 was performed. Data collected include participation in the ERAS protocol, patient demographics, length of stay (LOS), complications (minor and major), and 30-day reoperation rates. RESULTS: A total of 123 patients met the inclusion criteria, with 36 non-ERAS and 87 ERAS patients. ERAS patients had a shorter length of stay than non-ERAS patients (4.14 vs. 4.69, p = 0.049). Higher BMI patients progressively benefited from their involvement in an ERAS pathway: class I obese patients had an LOS decrease of 0.99 days (p = 0.048) and class II+ obese patients had an LOS decrease of 1.35 days (p = 0.093). Minor complications, major complications, and reoperation rates were similar between ERAS and non-ERAS patients (p>0.05). CONCLUSION: Utilization of an ERAS protocol for free flap breast reconstruction safely decreases LOS, especially with increasing BMI. Patients benefit from an ERAS protocol without increasing risk of postoperative complications, compared to non-ERAS patients of similar BMIs.


Assuntos
Recuperação Pós-Cirúrgica Melhorada/normas , Retalhos de Tecido Biológico , Mamoplastia , Obesidade , Complicações Pós-Operatórias , Reoperação , Adulto , Índice de Massa Corporal , Protocolos Clínicos , Feminino , Retalhos de Tecido Biológico/efeitos adversos , Retalhos de Tecido Biológico/estatística & dados numéricos , Humanos , Tempo de Internação/estatística & dados numéricos , Mamoplastia/efeitos adversos , Mamoplastia/métodos , Mamoplastia/reabilitação , Pessoa de Meia-Idade , Obesidade/diagnóstico , Obesidade/cirurgia , Avaliação de Processos e Resultados em Cuidados de Saúde , Aceitação pelo Paciente de Cuidados de Saúde , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/cirurgia , Reoperação/métodos , Reoperação/estatística & dados numéricos , Estudos Retrospectivos
6.
Eur J Surg Oncol ; 46(12): 2202-2207, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32807619

RESUMO

BACKGROUND: Autologous reconstruction after mastectomy became more and more popular, so this study aimed to obtain up-to-date and comprehensive data on autologous reconstruction in China. METHODS: An electronic questionnaire was sent to 110 hospitals, which were chosen depending on geographical distribution and hospital types. The questionnaire investigated the demographics, characteristics, breast cancer treatment and reconstruction situation of these hospitals through different modules. We only focused on the autologous breast reconstruction module data. RESULTS: 96 hospitals have performed breast reconstruction surgery. The proportion of the hospital performing latissimus dorsi flap (LDF, N = 91), pedicle transverse rectus abdominis myocutaneous flap (pTRAM, N = 62), free abdominal flap (N = 43) and other kinds of flap decreased in sequence. Of the overall reconstruction cases, only 34.3% were autologous reconstruction and LDF was still the most popular option for autologous reconstruction. Related factors of hospital performing different procedures included years of performing breast reconstruction, breast surgical volume, and establishment of an independent plastic surgery department. Compared with LDF, abdominal breast reconstruction was associated with a higher flap necrosis rate. CONCLUSIONS: This cross-sectional survey offers real-life autologous reconstruction information on a large population and covers the national surgical landscape in China. Autologous reconstruction is still an important part of breast reconstruction. Nevertheless, its low proportion and lower proportion of abdominal flap reconstruction in each institution, demonstrates that special training should be developed for breast surgeons and multidisciplinary cooperation would be promoted in the future.


Assuntos
Neoplasias da Mama/cirurgia , Retalhos de Tecido Biológico/estatística & dados numéricos , Hospitais/estatística & dados numéricos , Mamoplastia/métodos , Mastectomia/métodos , Retalho Miocutâneo/estatística & dados numéricos , Reto do Abdome/transplante , Músculos Superficiais do Dorso/transplante , Parede Abdominal , China , Estudos Transversais , Feminino , Departamentos Hospitalares/estatística & dados numéricos , Hospitais Gerais/estatística & dados numéricos , Hospitais com Alto Volume de Atendimentos/estatística & dados numéricos , Hospitais Especializados , Hospitais de Ensino/estatística & dados numéricos , Humanos , Modelos Logísticos , Cirurgia Plástica/estatística & dados numéricos , Retalhos Cirúrgicos/estatística & dados numéricos , Transplante Autólogo/estatística & dados numéricos
7.
J Surg Res ; 248: 165-170, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31923832

RESUMO

BACKGROUND: Microsurgical free tissue transfer is an important treatment option for nonhealing lower extremity diabetic wounds. The purpose of this study was to identify factors that affect flap survival and wound complications. METHODS: A retrospective review was conducted of 806 lower extremity free-flap reconstructions performed from 1979 to 2016. A total of 33 free flaps were used for coverage of nonhealing lower-extremity diabetic ulcers. Primary outcome measures were perioperative complications and long-term wound breakdown. RESULTS: The average age was 54 ± 12.3 y. 15.2% of patients were smokers, 12.1% had coronary artery disease and 12.1% had end-stage renal disease. Muscle flaps predominated (75.8%) compared to fasciocutaneous flaps (24.2%). There were 7 patients (21.2%) that underwent a revascularization procedure before (71.4%) or at the same time (28.6%) as the free flap. Immediate complications occurred in 7 flaps (21.2%) with 4 partial losses (12.1%) and 3 total flap failures (9.1%). Major wound complications occurred in 18.2% of patients. An end-to-side (E-S) anastomosis for the artery was used in 63.6% (n = 22) of flaps compared with an end-to-end (E-E) anastomosis. E-S anastomosis was associated with a significantly lower risk of wound complications compared with an arterial E-E anastomosis (0% versus 45.5%, P = 0.001). CONCLUSIONS: The use of microvascular free flaps can be used successfully to cover lower-extremity diabetic wounds. E-E arterial anastomosis should be avoided if possible as it is associated with higher rates of wound breakdown, likely by impairing perfusion to a distal limb with an already compromised vasculature. LEVEL OF EVIDENCE: Level III.


Assuntos
Pé Diabético/cirurgia , Retalhos de Tecido Biológico/estatística & dados numéricos , Salvamento de Membro/métodos , Adulto , Idoso , Feminino , Retalhos de Tecido Biológico/efeitos adversos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Deiscência da Ferida Operatória/etiologia
8.
Laryngoscope ; 130(3): 679-684, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31361334

RESUMO

BACKGROUND: Predictive models to forecast the likelihood of specific outcomes after surgical intervention allow informed shared decision-making by surgeons and patients. Previous studies have suggested that existing general surgical risk calculators poorly forecast head and neck surgical outcomes. However, no large study has addressed this question while subdividing subjects by surgery performed. OBJECTIVES: To determine the accuracy of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Surgical Risk Calculator in estimating length of hospital stay and risk of postoperative complications after free tissue transfer surgery. STUDY DESIGN: A retrospective chart review of patients at one institution was performed using Current Procedural Terminology codes for anterolateral thigh (ALT) flap, fibula free flap (FFF), and radial forearm free flap (RFFF) reconstruction. Output data from the ACS NSQIP surgical risk calculator were compared with the observed rates in our patients. METHODS: Incidences of cardiac complications, pneumonia, venous thromboembolism, return to the operating room, and discharge to skilled nursing facility (SNF) were compared to predicted incidences. Length of stay was also compared to the predicted length of stay. RESULTS: Three hundred thirty-six free flap reconstructions with 197 ALT flaps, 85 RFFFs, and 54 FFFFs were included. Brier scores were calculated using ACS NSQIP forecast and actual incidences. No Brier score was <0.01 for the entire sample or any subgroup, which indicates that the NSQIP risk calculator does not accurately forecast outcomes after free tissue reconstruction. CONCLUSION: The ACS NSQIP failed to accurately forecast postoperative outcomes after head and neck free flap reconstruction for the entire sample or subgroup analyses. LEVEL OF EVIDENCE: 4 Laryngoscope, 130:679-684, 2020.


Assuntos
Regras de Decisão Clínica , Retalhos de Tecido Biológico/estatística & dados numéricos , Procedimentos Cirúrgicos Otorrinolaringológicos/estatística & dados numéricos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Complicações Pós-Operatórias/etiologia , Idoso , Feminino , Previsões/métodos , Retalhos de Tecido Biológico/efeitos adversos , Humanos , Incidência , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Otorrinolaringológicos/efeitos adversos , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Complicações Pós-Operatórias/epidemiologia , Melhoria de Qualidade , Curva ROC , Procedimentos de Cirurgia Plástica/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Estudos Retrospectivos , Medição de Risco , Estados Unidos
9.
Jpn J Clin Oncol ; 50(2): 152-158, 2020 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-31670807

RESUMO

BACKGROUND: Sequential free flap reconstruction in patient with head and neck cancer can provide reliable and effective wound coverage. Only a few studies have reported on the outcome and complications analysis but without consensus on the recipient vessels and flap chosen. Herein, we presented the outcome and analysed the risk factors for complications in sequential free flap reconstruction. PATIENTS AND METHODS: Patients who had sequential free tissue transfers due to cancer recurrence, second primary cancer, or secondary correction of the soft tissue contractures and volume deficits were all included. Variables extracted included demographics, comorbidities, free flap characteristics, infection, dehiscence and flap necrosis rates. RESULTS: In total, 40 patients with 92 free flaps were analyzed; 42 initial and 50 sequential free flaps. The most common recipient vessels for sequential flap were contralateral superficial thyroid vessels (68%). The most common flap for both initial and sequential free flap was anterolateral thigh flap (64.3 and 62%). The success rate of sequential free flap was 92.0 compared to 92.9% for initial free flap, which showed no significant difference. Female was independently associated with delayed wound healing with an odds ratio of 90.91 (95% confidence interval 0.001-0.17, P = 0.001), as well as diabetes with an odds ratio of 31.14 (95% confidence interval 2.60-373.19, P = 0.007). Sequential free flap was not a risk factor for any complication. CONCLUSIONS: Sequential free flap is a reliable method for head and neck surgery without more complication rate comparing to initial free flap reconstruction. More attentions should be paid on patients with preferential risk for certain complications.


Assuntos
Retalhos de Tecido Biológico/transplante , Neoplasias de Cabeça e Pescoço/cirurgia , Neoplasias Bucais/cirurgia , Procedimentos de Cirurgia Plástica , Adulto , Idoso , Feminino , Retalhos de Tecido Biológico/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/métodos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Reoperação , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
10.
J Surg Oncol ; 121(3): 465-473, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31853992

RESUMO

BACKGROUND AND OBJECTIVES: The purpose of this study is to present our experience using free fillet flaps to reconstruct massive oncologic defects of the upper and lower extremity. METHODS: A retrospective chart review was performed to include patients who underwent oncologic resection followed by reconstruction using free fillet flaps from July 2001 to October 2018. Patient demographics, clinical and surgical characteristics, and postoperative complications were reviewed. RESULTS: In total, 12 patients were identified and included in this study. Mean age was 48.9 years old. Five patients had extended forequarter amputations and seven patients had external hemipelvectomies, all for locally advanced tumors. Mean tumor size was 15 ± SD 6.4 cm, and negative tumor margins were achieved in all the patients. Mean flap size was 1028 ± SD 869 cm2 . The mean follow-up was 13 months. There were no partial or total flap losses in the postoperative period. Two patients had flap-related postoperative complications, including flap bleeding and wound dehiscence. Median survival was 18 months. CONCLUSION: The free fillet flap is a safe, reliable, and valuable approach for reconstructing oncological defects. It offers the advantage of avoiding donor site morbidity, while providing extensive soft-tissue coverage as a one-step solution for massive oncologic defects.


Assuntos
Retalhos de Tecido Biológico/estatística & dados numéricos , Extremidade Inferior/cirurgia , Neoplasias/mortalidade , Neoplasias/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Complicações Pós-Operatórias , Retalhos Cirúrgicos/estatística & dados numéricos , Adulto , Feminino , Hemipelvectomia/mortalidade , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Procedimentos de Cirurgia Plástica/mortalidade , Estudos Retrospectivos , Taxa de Sobrevida , Resultado do Tratamento , Adulto Jovem
11.
J Plast Reconstr Aesthet Surg ; 72(12): 1930-1935, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31628083

RESUMO

INTRODUCTION: Autologous breast reconstruction, on its own, is a complex microsurgical procedure. However, this operation is usually just one of a series of steps along a patient's reconstructive journey. This includes not only a primary major surgical event but also the consequent recovery, potential complications and secondary surgeries required to optimise the final outcome. Unfortunately, there is limited information of what patients can expect from this reconstructive journey in the literature. The aim of this study was to characterise the journey of a consecutive cohort of patients through their whole reconstructive pathway in a high-volume UK-based breast reconstruction service. METHODS: A retrospective case analysis was undertaken including all the patients who had an autologous breast reconstruction at the Queen Victoria Hospital in East Grinstead between January 2012 and December 2014. Their case notes were reviewed from their initial referral to their final discharge. Number of operations, complication rates and time required to complete their journey were recorded, as well as differences between different flap options, immediate versus delayed and unilateral versus bilateral breast reconstructions. RESULTS: A total of 409 autologous breast reconstruction cases were performed in the 3-year study period. The vast majority of breast reconstructions used a deep inferior epigastric perforator flap (81.5%), with muscle-sparing transverse abdominal flaps (14.6%) and transverse upper gracilis flaps (3.9%) being the other options utilised. Free flap success was observed in 99.5% cases. Almost all patients opted for subsequent surgery (94%) of any kind. Only 75% opted for the reconstruction of their nipples. On average, 3.20 procedures were required per patient on this cohort, and these procedures were performed in 1.5 surgical episodes on average. Bilateral reconstructions reached the discharge point sooner than unilateral reconstructions and required a smaller number of operations. The average time to complete the reconstructive journey was 20.8 months. DISCUSSION: Patient-centred decision-making is fundamental to select the correct intervention for each patient and empower her in her healing journey. Standard measuring of patient satisfaction is still an unaccomplished goal in our unit.


Assuntos
Neoplasias da Mama/cirurgia , Mamoplastia/estatística & dados numéricos , Microcirurgia/estatística & dados numéricos , Adulto , Tomada de Decisão Clínica , Procedimentos Clínicos , Feminino , Retalhos de Tecido Biológico/estatística & dados numéricos , Hospitais com Alto Volume de Atendimentos/estatística & dados numéricos , Humanos , Tempo de Internação/estatística & dados numéricos , Londres , Mamoplastia/métodos , Microcirurgia/métodos , Mamilos/cirurgia , Participação do Paciente , Satisfação do Paciente , Retalho Perfurante/estatística & dados numéricos , Complicações Pós-Operatórias/etiologia , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Transplante Autólogo , Resultado do Tratamento , Neoplasias Unilaterais da Mama/cirurgia
12.
Breast Cancer Res Treat ; 178(1): 177-183, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31338643

RESUMO

INTRODUCTION: Despite the growing spotlight on value-based care and patient safety, little is known about the influence of patient-, reconstruction-, and facility-level factors on safety events following breast reconstruction. The purpose of this study is to characterize postoperative complications in light of hospital-level risk factors. METHODS: Using the National Inpatient Sample, all patients who underwent free flap and prosthetic breast reconstruction from 2012 to 2014 were identified. Predictor variables included patient demographic and clinical characteristics, type and timing of reconstruction, annual hospital reconstructive volume, hospital bed size, hospital setting (rural vs. urban), and length of stay. Patient safety indicators (PSIs) were based on the Agency for Healthcare Research and Quality's designation of preventable hospital complications: venous thromboembolism, bleeding, wound complications, pneumonia, and sepsis. Logistic models were used to analyze outcomes. RESULTS: The sample included 103,301 women, of which 27,695 (26.8%) underwent free flap reconstruction. 3.6% of patients experienced ≥ 1 PSI, most commonly wound PSI (4.9% and 2.5% for free flap and prosthetic reconstruction, respectively). Significant predictors of PSIs included rural setting (p < 0.01) and Elixhauser score ≥ 4 (p < 0.01) for the free flap group, and delayed reconstruction (p < 0.01) for the prosthetic group. Annual reconstructive facility volume was not associated with increased odds of PSIs in either prosthetic or free flap reconstruction (p > 0.05). CONCLUSION: PSIs were associated with rural hospitals and greater comorbidities for patients undergoing reconstruction with free flaps. Annual reconstructive facility volume was not associated with adverse inpatient outcomes with either method of reconstruction.


Assuntos
Neoplasias da Mama/cirurgia , Mamoplastia/métodos , Complicações Pós-Operatórias/epidemiologia , Feminino , Retalhos de Tecido Biológico/estatística & dados numéricos , Hospitais com Alto Volume de Atendimentos , Humanos , Tempo de Internação , Modelos Logísticos , Mamoplastia/estatística & dados numéricos , Mastectomia , Segurança do Paciente , Estudos Retrospectivos , Estados Unidos
13.
Plast Reconstr Surg ; 144(1): 12-20, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31246791

RESUMO

BACKGROUND: Pathogenic mutations have been identified in approximately 10 percent of patients who present with breast cancer. Notably, failure to identify deleterious genetic mutations has particular implications for patients undergoing abdominally based breast reconstruction, as the donor site can be used only once. The authors sought to determine: (1) how many patients underwent genetic testing before unilateral abdominally based free flap breast reconstruction; (2) how often deleterious mutations were detected after abdominally based free flap breast reconstruction; and (3) the cost-effectiveness of expanding genetic testing in this patient population. METHODS: The authors retrospectively identified all patients who underwent unilateral abdominally based free flap breast reconstruction at Brigham and Women's Hospital/Dana-Farber Cancer Institute between 2007 and 2016. Chart review was performed to collect relevant demographic and clinical data. Relevant hospital financial data were obtained. RESULTS: Of the 713 who underwent free flap breast reconstruction, 160 patients met inclusion criteria, and mean follow-up was 5.8 years. Three patients (1.9 percent of 160) underwent contralateral surgery after completing reconstruction, two of whom had BRCA2 and one with ATM mutation. One hundred eleven patients met National Comprehensive Cancer Network guidelines for genetic testing, but of those only 55.9 percent (62 patients) were tested. Financial data revealed that testing every patient in the cohort would result in a net savings of $262,000. CONCLUSIONS: During a relatively short follow-up period, a small percentage of patients were diagnosed with pathogenic mutations and underwent contralateral mastectomy and reconstruction. However, because of the costliness of surgery and the decreased cost of genetic testing, it is cost-effective to test every patient before unilateral abdominally based free flap breast reconstruction.


Assuntos
Neoplasias da Mama/genética , Predisposição Genética para Doença/genética , Mutação/genética , Adulto , Idoso , Proteínas Mutadas de Ataxia Telangiectasia/genética , Proteína BRCA2/genética , Neoplasias da Mama/cirurgia , Quinase do Ponto de Checagem 2/genética , Atenção à Saúde , Proteínas de Grupos de Complementação da Anemia de Fanconi/genética , Feminino , Retalhos de Tecido Biológico/estatística & dados numéricos , Testes Genéticos , Humanos , Mamoplastia/métodos , Mastectomia/métodos , Pessoa de Meia-Idade , RNA Helicases/genética , Estudos Retrospectivos , Ubiquitina-Proteína Ligases/genética
14.
Laryngoscope ; 129(1): 138-145, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30194763

RESUMO

OBJECTIVES/HYPOTHESIS: Despite major advances in the field of head and neck microvascular free tissue transfer (MFTT) over the past several decades, there are no standardized perioperative regimens for the care of patients undergoing free flap reconstructive surgery, and continued variation in practice exists. This study aimed to report current trends in the field of MFTT performed by otolaryngologists, including surgeon training, institutional operative practices, and perioperative management. STUDY DESIGN: Cross-sectional survey. METHODS: A survey of Accreditation Council for Graduate Medical Education-accredited residency programs and American Head and Neck Society fellowship sites was conducted. RESULTS: Seventy-one (62.8%) programs responded, with 67 (94.4%) routinely performing MFTT and 23 (32.4%) having a dedicated microvascular fellowship program. Of institutions performing MFTT, 66 (98.5%) reported the use of a two-surgeon team, most commonly both otolaryngologists (76.3%). Institutional MFTT volumes and donor site frequency are reported. Postoperative care includes routine admission to the intensive care unit (75.2%), step-down unit (15.0%), or general care floor (8.1%). Postoperative flap monitoring practices, including modalities, personnel, and timing/frequency show institutional variation. Despite differences in postoperative monitoring regimen and management (sedation, anticoagulation, antibiotic use), surgeon-reported measures of flap success rate (95.7%, standard deviation [SD] 4.7%) and complication rate (6.8%, SD 2.4%) show little difference across institutions. CONCLUSIONS: Many elements of MFTT perioperative care show continued variation at an institutional level. There is a notable shift toward the two-team approach within otolaryngology. Self-reported flap complication and success rates showed no significant differences based on perioperative care and monitoring regimen. Further study of perioperative practices should focus on standardization of care to improve overall outcomes in this complex patient population. LEVEL OF EVIDENCE: NA Laryngoscope, 129:138-145, 2019.


Assuntos
Retalhos de Tecido Biológico , Neoplasias de Cabeça e Pescoço/cirurgia , Otolaringologia/educação , Procedimentos Cirúrgicos Otorrinolaringológicos/métodos , Procedimentos de Cirurgia Plástica/métodos , Canadá , Estudos Transversais , Educação de Pós-Graduação em Medicina , Retalhos de Tecido Biológico/estatística & dados numéricos , Humanos , Procedimentos Cirúrgicos Otorrinolaringológicos/educação , Procedimentos de Cirurgia Plástica/educação , Estados Unidos
15.
J Craniofac Surg ; 30(1): 178-183, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30394970

RESUMO

BACKGROUND: Contradictory data exists on the success rates of employing the external jugular (EJ) vein as a recipient vessel for venous outflow in free flap head and neck reconstruction compared with the internal jugular (IJ) vein. The authors hereby present a retrospective study of prospectively collected data over a 14-year period. METHODS: Five hundred seventy-eight patients underwent 639 free flap head and neck over 14 years. Two hundred seventy-eight free flaps employed the EJ vein as the recipient vessel while 326 free flaps employed the IJ vein. Rates of acute and late complications were compared. RESULTS: There were no differences in rates of complications: flap loss, venous thrombosis, arterial thrombosis, bleeding, hematoma, or infection between the EJ and IJ vein groups. CONCLUSION: The external jugular vein as a recipient vessel for venous outflow in head and neck free flap reconstruction of postoncologic resection defects is a valid option for both primary reconstructions and secondary surgeries.


Assuntos
Retalhos de Tecido Biológico , Veias Jugulares , Retalhos de Tecido Biológico/efeitos adversos , Retalhos de Tecido Biológico/irrigação sanguínea , Retalhos de Tecido Biológico/estatística & dados numéricos , Retalhos de Tecido Biológico/cirurgia , Humanos , Veias Jugulares/cirurgia , Veias Jugulares/transplante , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Resultado do Tratamento
16.
Plast Reconstr Surg ; 142(6): 1438-1446, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30489515

RESUMO

BACKGROUND: Market competition is believed to promote patient access and health care delivery. The authors examined the relationship between market competition and use of surgical services for cancer, using free flap immediate breast reconstruction as a model scenario. METHODS: This retrospective cross-sectional analysis of the 2008 to 2011 Nationwide Inpatient Sample identified female patients undergoing immediate breast reconstruction. The Herfindahl-Hirschman Index was used to describe hospital markets as competitive or consolidated. The relationship between market competition and free flap immediate breast reconstruction use was explored using a hierarchical model before and after race stratification. RESULTS: Seven thousand three hundred seventy-two (10.7 percent) of 68,966 patients underwent free flap immediate breast reconstruction. A consolidated market was associated with 35 percent lower odds of free flap immediate breast reconstruction (95 percent CI, 0.43 to 0.97). Undergoing an operation in a later year [OR, 1.40; 95 percent CI (per year), 1.21 to 1.63], nonwhite race (OR, 1.33; 95 percent CI, 1.10 to 1.60), private insurance (OR, 2.09; 95 percent CI, 1.59 to 2.76), and teaching hospital status (OR, 2.67; 95 percent CI, 1.73 to 4.13) were associated with higher rates of free flap reconstruction. Market consolidation was associated with 48 percent lower odds of undergoing free flap immediate breast reconstruction in nonwhite patients only (95 percent CI, 0.29 to 0.92). CONCLUSIONS: A hospital's willingness to provide surgical services may be subject to market pressures. Market competition is associated with increased odds of free flap immediate breast reconstruction and higher use by racial minorities.


Assuntos
Neoplasias da Mama/cirurgia , Retalhos de Tecido Biológico/estatística & dados numéricos , Mamoplastia/estatística & dados numéricos , Neoplasias da Mama/economia , Estudos Transversais , Atenção à Saúde/economia , Atenção à Saúde/estatística & dados numéricos , Competição Econômica , Economia Hospitalar , Utilização de Equipamentos e Suprimentos , Feminino , Retalhos de Tecido Biológico/economia , Hospitalização/economia , Hospitalização/estatística & dados numéricos , Hospitais/estatística & dados numéricos , Humanos , Cobertura do Seguro/estatística & dados numéricos , Seguro Saúde/estatística & dados numéricos , Mamoplastia/economia , Marketing de Serviços de Saúde/economia , Marketing de Serviços de Saúde/estatística & dados numéricos , Mastectomia/economia , Mastectomia/estatística & dados numéricos , Pessoa de Meia-Idade , Grupos Raciais/estatística & dados numéricos , Estudos Retrospectivos , Estados Unidos
17.
Plast Reconstr Surg ; 142(4): 434e-442e, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29979366

RESUMO

BACKGROUND: Flap-based breast reconstruction demands greater operative labor and offers superior patient-reported outcomes compared with implants. However, use of implants continues to outpace flaps, with some suggesting inadequate remuneration as one barrier. This study aims to characterize market variation in the ratio of implants to flaps and assess correlation with physician payments. METHODS: Using the Blue Health Intelligence database from 2009 to 2013, patients were identified who underwent tissue expander (i.e., implant) or free-flap breast reconstruction. The implant-to-flap ratio and physician payments were assessed using quadratic modeling. Matched bootstrapped samples from the early and late periods generated probability distributions, approximating the odds of surgeons switching reconstructive method. RESULTS: A total of 21,259 episodes of breast reconstruction occurred in 122 U.S. markets. The distribution of implant-to-flap ratio varied by market, ranging from the fifth percentile at 1.63 to the ninety-fifth percentile at 43.7 (median, 6.19). Modeling the implant-to-flap ratio versus implant payment showed a more elastic quadratic equation compared with the function for flap-to-implant ratio versus flap payment. Probability modeling demonstrated that switching the reconstructive method from implants to flaps with a 0.75 probability required a $1610 payment increase, whereas switching from flaps to implants at the same certainty occurred at a loss of $960. CONCLUSIONS: There was a correlation between the ratio of flaps to implants and physician reimbursement by market. Switching from implants to flaps required large surgeon payment increases. Despite a relative value unit schedule over twice as high for flaps, current flap reimbursements do not appear commensurate with physician effort.


Assuntos
Implantes de Mama/estatística & dados numéricos , Retalhos de Tecido Biológico/estatística & dados numéricos , Reembolso de Seguro de Saúde/estatística & dados numéricos , Mamoplastia/economia , Adulto , Planos de Seguro Blue Cross Blue Shield/estatística & dados numéricos , Feminino , Humanos , Revisão da Utilização de Seguros , Mamoplastia/métodos , Mamoplastia/estatística & dados numéricos , Pessoa de Meia-Idade , Dispositivos para Expansão de Tecidos/estatística & dados numéricos , Estados Unidos
18.
Plast Reconstr Surg ; 141(4): 493e-499e, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29595721

RESUMO

BACKGROUND: Prosthetic breast reconstruction rates have risen in the United States, whereas autologous techniques have stagnated. Meanwhile, single-institution data demonstrate that physician payments for prosthetic reconstruction are rising, while payments for autologous techniques are unchanged. This study aims to assess payment trends and variation for tissue expander and free flap breast reconstruction. METHODS: The Blue Health Intelligence database was queried from 2009 to 2013, identifying women with claims for breast reconstruction. Trends in the incidence of surgery and physician reimbursement were characterized by method and year using regression models. RESULTS: There were 21,259 episodes of breast reconstruction, with a significant rise in tissue expander cases (incidence rate ratio, 1.09; p < 0.001) and an unchanged incidence of free flap cases (incidence rate ratio, 1.02; p = 0.222). Bilateral tissue expander cases reimbursed 1.32 times more than unilateral tissue expanders, whereas bilateral free flaps reimbursed 1.61 times more than unilateral variants. The total growth in adjusted tissue expander mean payments was 6.5 percent (from $2232 to $2378) compared with -1.8 percent (from $3858 to $3788) for free flaps. Linear modeling showed significant increases for tissue expander reimbursements only. Surgeon payments varied more for free flaps (the 25th to 75th percentile interquartile range was $2243 for free flaps versus $987 for tissue expanders). CONCLUSIONS: The incidence of tissue expander cases and reimbursements rose over a period where the incidence of free flap cases and reimbursements plateaued. Reasons for stagnation in free flaps are unclear; however, the opportunity cost of performing this procedure may incentivize the alternative technique. Greater payment variation in autologous reconstruction suggests the opportunity for negotiation with payers.


Assuntos
Reembolso de Seguro de Saúde/tendências , Mamoplastia/economia , Mamoplastia/métodos , Padrões de Prática Médica/economia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Implantes de Mama/economia , Implantes de Mama/estatística & dados numéricos , Bases de Dados Factuais , Feminino , Retalhos de Tecido Biológico/economia , Retalhos de Tecido Biológico/estatística & dados numéricos , Humanos , Modelos Lineares , Mamoplastia/instrumentação , Mamoplastia/tendências , Pessoa de Meia-Idade , Padrões de Prática Médica/tendências , Expansão de Tecido/economia , Expansão de Tecido/instrumentação , Expansão de Tecido/tendências , Dispositivos para Expansão de Tecidos/economia , Dispositivos para Expansão de Tecidos/estatística & dados numéricos , Estados Unidos , Adulto Jovem
19.
Int J Oral Maxillofac Surg ; 47(5): 676-682, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29275838

RESUMO

Free flap surgery is essential for the aesthetic and functional reconstruction of various parts of the body. The aim of this study was to compare current concepts of perioperative flap management between ENT, craniomaxillofacial, and plastic surgeons. A European survey was conducted among 570 surgical departments, covering all aspects of free flap surgery. Focus was placed on antibiotic and antithrombotic drug use, aspects of osseous reconstruction, and flap monitoring strategies. One hundred and seventy-two medical units participated. A broad spectrum of anticoagulant regimens and a trend towards prolonged antibiotic prophylaxis were found. Fixation with (CAD/CAM) reconstruction plates was more popular than monocortical locking with miniplates in the mandible. Visual assessment and Doppler systems were reported to be the most common monitoring modalities. The flap loss rate was stated to be higher after osseous reconstruction. Only a few differences in perioperative flap management were identified between the different surgical fields, and osseous reconstruction appears to be the most challenging.


Assuntos
Retalhos de Tecido Biológico/estatística & dados numéricos , Cirurgia Ortognática , Otolaringologia , Padrões de Prática Médica/estatística & dados numéricos , Cirurgia Plástica , Antibioticoprofilaxia , Anticoagulantes/uso terapêutico , Desenho Assistido por Computador , Diagnóstico por Imagem , Europa (Continente) , Sobrevivência de Enxerto , Humanos , Fixadores Internos , Inquéritos e Questionários
20.
Acta méd. costarric ; 59(3): 110-112, jul.-sep. 2017. ilus
Artigo em Espanhol | LILACS | ID: biblio-886380

RESUMO

ResumenEl pene tradicionalmente se ha considerado un símbolo de poder, masculinidad y fertilidad, por lo cual toda patología peniana congénita o adquirida, que eventualmente culmine en la amputación parcial o total del falo, constituye un evento catastrófico para cualquier hombre, presentando efectos devastadores, tanto físicos como psicológicos. Los diferentes niveles de amputación peniana en un individuo pueden definir su capacidad de miccionar y de concretar el coito, lo que perjudica directamente su virilidad y desempeño sexual y, por ende, su bienestar psicológico. Todo esto justifica el esfuerzo reconstructivo que se pueda ofrecer con el fin de mejorar la calidad de vida del paciente. El colgajo libre radial de antebrazo se ha considerado por muchos años el estándar de oro en reconstrucción peniana, ya que ha demostrado buenos resultados funcionales y estéticos. Esta técnica microquirúrgica representa un gran avance reconstructivo, lo cual se traduce en un rescate de la autoestima y de la masculinidad del paciente, con mejoría significativa de su calidad de vida. A continuación se presenta el caso clínico de un paciente masculino de 35 años de edad, quien requirió una amputación casi total de pene, secundaria a una quemadura eléctrica severa, y posteriormente fue sometido a la primera reconstrucción peniana microquirúrgica con colgajo libre radial de antebrazo, en Costa Rica.


AbstractThe penis has traditionally been considered a symbol of power, masculinity and fertility, so any congenital or acquired penile pathology that eventually culminates in partial or total amputation of the phallus constitutes a catastrophic event for any man, presenting both physical and psychological devastating effects. The different levels of penile amputation in an individual can define their ability to micturate and to concretize sexual intercourse, which directly impairs their virility and sexual performance and thus their psychological well-being. All this finally justifies any reconstructive effort that can be offered in order to improve the patient's quality of life. The free radial forearm flap has been considered for many years the gold standard in penile reconstruction as it has demonstrated good functional and aesthetic results. This microsurgical technique represents a great reconstructive advance, which results in a rescue of the patient's self-esteem and masculinity with a significant improvement in his quality of life. The authors present the clinical case of a 35-year-old male patient who required an almost total amputation of the penis, secondary to a severe electrical burn and who subsequently underwent the first microsurgical penile reconstruction with a free radial forearm flap in Costa Rica.


Assuntos
Humanos , Masculino , Retalhos de Tecido Biológico/estatística & dados numéricos , Microcirurgia/estatística & dados numéricos , Pênis/cirurgia , Costa Rica
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